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Cheesy Sour Cream Chicken Casserole Recipe

Cheesy Sour Cream Chicken Casserole Recipe


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4.8 from 21 reviews

  • Total Time: 1 hour 15 minutes
  • Yield: 4 1x

Description

Comforting Cheesy Sour Cream Chicken Casserole brings Southern kitchen warmth to dinner tables with creamy, golden layers of tender chicken and melted cheese. Hearty ingredients merge into a crowd-pleasing meal you’ll savor from first to last delicious bite.


Ingredients

Scale

Main Proteins:

  • 4 boneless, skinless chicken breasts (about 1.4 kg / 3 pounds)

Cheeses:

  • ¾ cup (180 ml) finely shredded Parmesan cheese
  • 4 slices mozzarella cheese

Seasonings and Binding Ingredients:

  • 1 tablespoon cornstarch
  • 1 teaspoon garlic powder
  • 1 teaspoon dried oregano
  • 1 pinch of salt
  • 1 pinch of black pepper
  • 1 cup (240 ml) rich sour cream
  • Cooking oil (for greasing the dish)

Instructions

  1. Preheat the oven to 375°F (190°C) and thoroughly grease a 9×13-inch (23×33 centimeters) baking dish with cooking spray or olive oil.
  2. Place the chicken breasts in a single layer within the prepared baking dish, then season generously with kosher salt and freshly ground black pepper to enhance the overall flavor profile.
  3. In a medium mixing bowl, whisk together sour cream, grated Parmesan cheese, dried oregano, garlic powder, cornstarch, additional salt, and cracked black pepper until the mixture becomes completely smooth and well-integrated.
  4. Layer a slice of mozzarella cheese directly onto each chicken breast, creating a delectable cheese foundation.
  5. Carefully spread the prepared sour cream mixture evenly across the mozzarella-topped chicken, ensuring complete coverage.
  6. Sprinkle the remaining Parmesan cheese over the top, creating a golden, crispy cheese crust.
  7. Transfer the baking dish to the preheated oven and bake for 50-60 minutes, or until the chicken reaches an internal temperature of 165°F (74°C) and the cheese turns bubbly and golden brown.
  8. Remove the casserole from the oven and let it rest for 5-7 minutes, allowing the sauce to thicken and flavors to meld together.
  9. Garnish with finely chopped fresh parsley or chives to add a bright, herbaceous note before serving the dish warm.

Notes

  • Leftover chicken transforms into a creamy, cheesy dream with minimal kitchen effort.
  • Customize spice levels by adjusting garlic powder and pepper to match personal taste preferences.
  • Cornstarch acts as a secret weapon, creating a luxuriously thick and smooth sauce that clings perfectly to chicken.
  • Mozzarella and Parmesan cheese combination delivers a decadent, rich flavor profile that elevates this simple casserole.
  • Fresh herbs like parsley or chives provide a bright, fresh finishing touch that cuts through the richness of the dish.
  • Prep Time: 15 minutes
  • Cook Time: 1 hour
  • Category: Dinner, Lunch
  • Method: Baking
  • Cuisine: American

Nutrition

  • Serving Size: 4
  • Calories: 464 kcal
  • Sugar: 2g
  • Sodium: 823 mg
  • Fat: 28g
  • Saturated Fat: 13g
  • Unsaturated Fat: 12g
  • Trans Fat: 0g
  • Carbohydrates: 7g
  • Fiber: <1g
  • Protein: 44g
  • Cholesterol: 152mg