The Perfect Chicken, Mushroom, and Spinach Lasagna Recipe You’ll Love

Chicken, mushroom, and spinach lasagna reimagines ordinary ingredients into an extraordinary culinary experience.

Hearty layers of succulent proteins intermingle with earthy woodland elements and verdant greens.

Soft textures and robust flavors dance across each carefully constructed section of this comforting dish.

Mediterranean-inspired ingredients create a harmonious blend that speaks to soul-warming nutrition.

Nutritious components marry effortlessly, generating depth and complexity beyond standard pasta preparations.

Carefully balanced seasonings elevate this classic comfort food into something truly remarkable.

You’ll find yourself craving every luxurious, warmth-filled bite.

Secrets for the Best Chicken, Mushroom, and Spinach Lasagna

• Master the Mushroom Sauté: Ensure high heat and avoid overcrowding the pan to achieve perfectly caramelized mushrooms with deep, rich flavor.
• Create Silky Smooth Sauce: Whisk the slurry carefully to prevent lumps, stirring constantly for a velvety, lump-free béchamel that coats every layer.
• Layer Like a Pro: Use a light touch when adding layers, pressing gently to eliminate air pockets and ensure even distribution of ingredients.
• Cheese Melting Magic: Grate fresh Parmesan and mozzarella for maximum flavor and optimal melting that creates those irresistible golden, bubbly edges.
• Foil Cover Technique: Tent the foil slightly above the lasagna's surface to prevent cheese from sticking and maintain moisture during initial baking.

Store and Reheat Chicken, Mushroom, and Spinach Lasagna the Right Way

• Refrigeration: Carefully transfer leftover lasagna into an airtight container or wrap tightly with plastic wrap. Store in the refrigerator for up to 3-4 days. The sealed container prevents moisture loss and keeps flavors intact.
• Freezing: Wrap individual portions or the entire lasagna in plastic wrap, then cover with aluminum foil for extra protection. Freeze for up to 2 months. Label the container with the date to track freshness.
• Reheating: Thaw frozen lasagna in the refrigerator overnight. Preheat the oven to 350°F (175°C). Place the lasagna in an oven-safe dish, cover with foil to prevent drying out, and warm for 20-25 minutes.

What to Serve with Chicken, Mushroom, and Spinach Lasagna

• Pair with Crisp White Wine: A chardonnay or sauvignon blanc cuts through the creamy lasagna's richness, balancing the dish's robust flavors with its bright, zesty notes.
• Serve with Fresh Green Salad: A light arugula salad dressed in lemon vinaigrette provides a tangy contrast to the lasagna's hearty texture, adding a refreshing element to the meal.
• Complement with Herbal Iced Tea: A rosemary or thyme-infused iced tea echoes the herbs in the lasagna, creating a harmonious flavor profile that enhances the overall dining experience.
• Finish with Rustic Bread: A crusty sourdough or ciabatta helps soak up the delicious sauce, providing an extra layer of texture and allowing diners to savor every last bit of the creamy chicken and mushroom mixture.

Fresh Spins on Chicken, Mushroom, and Spinach Lasagna

• Veggie Lover's Delight: Replace chicken with extra firm tofu or plant-based protein crumbles for a vegetarian version that maintains the creamy texture and rich flavors.
• Mediterranean Medley: Swap out traditional herbs for fresh thyme, rosemary, and add sun-dried tomatoes and crumbled feta cheese to give the lasagna a Greek-inspired profile.
• Seafood Special: Substitute chicken with tender shrimp or crab meat, using white fish stock instead of chicken stock to create a luxurious ocean-inspired lasagna that highlights delicate seafood flavors.
• Spicy Southwest Style: Incorporate diced green chiles, swap basil for cilantro, and use pepper jack cheese to transform the recipe into a zesty, southwestern-inspired lasagna with a kick of heat.

Why Chicken, Mushroom, and Spinach Lasagna Is Worth Making

• Craft a Comforting One-Pot Wonder: This lasagna transforms simple ingredients into a soul-warming meal that combines protein-packed chicken, earthy mushrooms, and nutrient-rich spinach in one delicious layered dish.
• Master Easy Layering Technique: Discover a foolproof method of creating restaurant-quality lasagna at home with straightforward steps that guarantee perfectly balanced flavors and textures in every bite.
• Enjoy Nutritional Powerhouse Meal: Packed with 30g of protein, this lasagna delivers a balanced nutrition profile while satisfying hunger with minimal prep time and maximum flavor, making it ideal for busy weeknight dinners or weekend gatherings.
• Create Versatile Crowd-Pleaser: The recipe offers flexible customization options, allowing home cooks to adjust seasonings or swap ingredients while maintaining a consistent, delightful taste that appeals to various palates.

All the Goodies in Chicken, Mushroom, and Spinach Lasagna

Main Ingredients:

• Chicken: Lean protein that adds substance and flavor to the lasagna.
• Mushrooms: Earthy fungi that provide depth and meaty texture to the dish.
• Spinach: Nutrient-rich green that adds color and wholesome nutrition.

• Mozzarella Cheese: Creamy cheese that melts beautifully and creates a rich topping.
• Parmesan Cheese: Sharp, aged cheese that enhances the overall flavor profile.

• Chicken Stock: Foundational liquid that builds depth and richness in the sauce.
• Milk: Smooth base that helps create a creamy and velvety sauce texture.

• Basil, Oregano: Classic Italian herbs that provide aromatic and traditional flavors.
• Red Pepper Flakes: Adds a subtle heat and slight kick to the dish.
• Nutmeg: Warm spice that complements the creamy sauce.

• Flour: Thickens the sauce and helps create a smooth consistency.
• Lasagna Noodles: Structural base that holds all ingredients together.

• Onions, Garlic: Aromatics that build a flavor foundation for the entire dish.
• Salt: Enhances and balances all the other flavors.

• Oil: Prevents sticking and helps sauté ingredients evenly.

Chicken, Mushroom, and Spinach Lasagna: Step-by-Step Guide

Step 1: Prepare the Oven

Preheat your oven to 375°F (190°C) to create the perfect cooking environment.

Step 2: Sauté the Vegetables and Spices

• Oil
• Onions
• Garlic
• Mushrooms
• Basil
• Oregano
• Red pepper flakes
• Salt

Sauté for about 5 minutes until the mixture becomes wonderfully fragrant.

Step 3: Add Spinach and Chicken

Toss in the spinach and cook until it wilts. Remove from heat and gently fold in chicken pieces, ensuring they’re well integrated with the vegetables.

Step 4: Create the Slurry

In a separate bowl, whisk of chicken stock with flour until smooth and lump-free.

Step 5: Prepare the Sauce Base

• Remaining chicken stock
• Milk
• Nutmeg
• Salt

Bring the mixture to a gentle simmer.

Step 6: Thicken and Enhance the Sauce

Slowly stir in the prepared slurry and continue cooking until the sauce slightly thickens. Mix in Parmesan cheese until completely melted and smooth.

Step 7: Layer the Lasagna

• Start with a thin layer of sauce
• Add lasagna noodles
• Spread chicken and vegetable mixture
• Sprinkle mozzarella cheese

Repeat the layering, ensuring the top layer is covered with cheese.

Step 8: Cover and Initial Baking

Tightly cover the dish with foil and bake for 25 minutes, trapping in all the delicious moisture.

Step 9: Finish with a Golden Crisp

Remove the foil and bake for an additional 15 minutes. For an extra crispy top, broil briefly (2-3 seconds) while watching carefully to prevent burning.

Step 10: Rest and Serve

Allow the lasagna to rest for a few minutes after removing from the oven. Slice and serve warm, enjoying the blend of flavors and textures.

Chicken, Mushroom, and Spinach Lasagna Recipe

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4.8 from 9 reviews

• Total Time: 1 hour 5 minutes
• Yield: 6 1x

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Description

Layers of comfort define this chicken, mushroom, and spinach lasagna, blending Italian culinary traditions with hearty ingredients. Creamy béchamel, tender chicken, earthy mushrooms, and nutritious spinach create a delightful harmony that will satisfy your craving for a rich, comforting meal.

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Ingredients

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Proteins:

• 2 cups shredded cooked chicken
• 1.25 cups shredded mozzarella cheese
• 0.5 cups shredded Parmesan cheese

Vegetables and Herbs:

• 8 ounces (226 grams) white mushrooms, thinly sliced
• 6 ounces (170 grams) bag fresh baby spinach
• 1 cup chopped onion
• 2 tablespoons minced garlic
• 1 teaspoon dried basil
• 1 teaspoon dried oregano
• 0.25 teaspoon nutmeg
• 0.5 teaspoon red pepper flakes

Liquids and Dry Ingredients:

• 2.5 tablespoons olive oil
• 2 cups whole milk
• 0.25 cup all-purpose flour
• 2 cups low-sodium chicken stock
• 1.25 teaspoons kosher salt
• 8 no-boil lasagna noodles

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Instructions

1. Ignite the oven to 375°F (190°C) to create an ideal cooking environment for the lasagna.
2. Activate a large sauté pan over medium-high heat, drizzling olive oil and introducing diced onions, minced garlic, sliced mushrooms, dried basil, oregano, red pepper flakes, and a pinch of salt. Sauté the aromatic ingredients for approximately 5 minutes until they release their fragrant essence.
3. Gently fold fresh spinach leaves into the vegetable medley, allowing them to wilt briefly. Remove from heat and integrate tender chicken pieces, ensuring thorough distribution throughout the mixture.
4. Craft a smooth slurry by whisking ½ cup of chicken stock with all-purpose flour in a separate mixing bowl until completely smooth and free of lumps.
5. In a companion saucepan, combine remaining chicken stock, whole milk, and a delicate hint of ground nutmeg, seasoning with of salt. Bring the liquid to a gentle simmer, creating a velvety base.
6. Gradually introduce the prepared flour slurry into the simmering liquid, stirring continuously until the sauce thickens slightly. Fold in freshly grated Parmesan cheese, allowing it to melt completely and create a rich, creamy consistency.
7. Select a 10×10 inch (25×25 centimeters) baking dish and begin layering: first, spread a thin layer of sauce across the bottom, then arrange lasagna noodles as a foundation. Distribute the chicken and vegetable blend evenly, followed by a generous sprinkle of shredded mozzarella cheese. Repeat the layering process, ensuring the final layer is topped with an abundant cheese covering.
8. Carefully shield the assembled lasagna with aluminum foil, creating a tight seal to preserve moisture during the initial baking phase of approximately 25 minutes.
9. After the covered baking period, remove the foil and return the dish to the oven. Bake for an additional 15 minutes, allowing the edges to transform into a golden-brown hue. For an extra crispy top, briefly activate the broiler, watching vigilantly to prevent burning.
10. Extract the lasagna from the oven and allow it to rest for 10-15 minutes, enabling the layers to set and making serving easier. Slice into portions and serve while still warm, revealing the beautiful layered composition.

Notes

• Embrace the flexibility of ingredient swaps, allowing home cooks to personalize this lasagna with alternative proteins like turkey or tofu.
• Maximize flavor development by allowing the sautéed vegetables to caramelize slightly before adding chicken, enhancing depth and richness.
• Prevent soggy lasagna by patting chicken and spinach dry, reducing excess moisture that could compromise the dish’s structural integrity.
• Consider make-ahead strategies: assemble the lasagna up to 24 hours in advance and refrigerate, then bake when ready to serve for convenience.
• Store leftovers in an airtight container within the refrigerator for up to three days, reheating gently to maintain moisture and prevent dried-out edges.

• Prep Time: 20 minutes
• Cook Time: 45 minutes
• Category: Dinner
• Method: Baking
• Cuisine: Italian

Nutrition

• Serving Size: 6
• Calories: 450 kcal
• Sugar: 4 g
• Sodium: 600 mg
• Fat: 20 g
• Saturated Fat: 10 g
• Unsaturated Fat: 7 g
• Trans Fat: 0 g
• Carbohydrates: 45 g
• Fiber: 2 g
• Protein: 30 g
• Cholesterol: 80 mg